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Cholesterol Drug May Prevent Colon Cancer – Hunterdon Healthcare

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Last updated 3 hours 7 minutes ago

A new National Cancer Institute (NCI) sponsored study evaluates the cholesterol drug, Rosuvastatin, (Crestor) as a treatment to reduce the risk of colon cancer.? Rosuvastatin is a statin, a class of drugs that lower cholesterol.? The study, titled, ?P-5: Statin Polyp Prevention Trial in Patients with Resected Colon Cancer,? is being conducted by a network of cancer research professionals, the National Surgical Adjuvant Breast and Bowel Project (NSABP), at 200 medical centers located throughout North America.

The study was developed because laboratory research and studies conducted in large populations of patients taking a statin to reduce cholesterol suggest that taking the drug may, also, decrease the number of colon polyps. ?Colon polyps can lead to colon cancer if left untreated.?

The study will involve 1,740 patients, who have recently been diagnosed with early stage colon cancer, and who were not already taking statins for high cholesterol.? Patients will be randomly assigned to one of two groups.? Each group will take one pill a day for five years.? One group?will receive Rosuvastatin, while the other group will receive a placebo.

?There will be an estimated 102,900 new cases of colon cancer in the United States this year.? In fact, colorectal cancer is the third most common cancer found in men and women in this country.?? We hope this trial will be an important step in reducing these numbers,? said Norman Wolmark, M.D., NSABP?s Chairman.

?Research in this area is critical because colorectal cancer continues to be a major health care problem associated with high mortality in the U.S. and around the world. New and more effective ways of preventing this malignancy are clearly needed. Determining whether statins lower cancer risk, including colorectal cancer risk, is of paramount importance, ?said Dr. Myron Bednar, Director or Clinical Research at Hunterdon Regional Cancer Center.

People recently diagnosed with a Stage I or II colon cancer who are interested in the study should contact the research department at Hunterdon Regional Cancer Center at 908-237-2330.? A list of other sites in North America that are participating in the study may be found at http://www.nsabp.pitt.edu/P5_Sites.asp

Since its beginning more than 50 years ago, NSABP has enrolled more than 140,000 women and men in clinical trials in breast and colorectal cancer.? NSABP has research sites at major medical centers, university hospitals, large oncology practice groups, and health maintenance organizations in the U.S., Canada, Puerto Rico, Australia and Ireland.? At those sites and their?satellites, more than 5,000 physicians, nurses and other medical professionals conduct NSABP treatment and prevention studies.

For more information regarding the eligibility criteria for this research study or to find out more about cancer clinical trials at Hunterdon Regional Cancer Center, please contact Rene Falls, RN, OCN, Clinical Research Nurse at (908)-237-2330 ext.2 or Lynda Poff, RN, OCN, Clinical Research Nurse at (908)-237-2330 ext.4.

Source: http://www.hunterdon-healthcare.com/513953/2012/08/06/cholesterol-drug-may-prevent-colon-cancer.html

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